Magnesium and left ventricular hypertrophy.

agnesium (Mg) is involved in many important enzymatic processes, electrolyte balance, and skeletal metabolism. Clinically, Mg plays an important role in the regulation of vascular tone and heart rhythm, prevention of thrombosis, atherosclerosis, insulin resistance, arrhythmia, and osteoporosis, suppression of inflammation, etc (Figure).1–3 Furthermore, hypermagnesemia inhibits parathyroid hormone secretion, which is considered to be an independent important risk factor for vascular calcification, left ventricular hypertrophy (LVH) and mortality in endstage renal disease (ESRD) patients.4